Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction) by blocking a certain enzyme (phosphodiesterase-PDE5) in the body.

This medicine is taken orally as needed, at least 30 minutes, but not more than 4 hours before sexual activity (one hour before it is most effective). Do not take more often than once a day and take as directed. A high-fat meal may delay the onset of this medication. Avoid eating grapefruit or drinking grapefruit juice while you are being treated with this medicine, unless your doctor tells you otherwise. The dosage is based on your medical condition, response to therapy, and other medications you are taking.

SP Agra should not be used with the following medicines as very serious (possibly lethal) interactions may occur: nitrates (eg nitroglycerin, isosorbide), nitropruside (or any “nitric oxide donor”), recreational medicines called “poppers” or nitrite of butyl. If you are taking an HIV protease inhibitor (eg ritonavir, saquinavir), do not take more than one dose of 25 mg SP Agra over a period of 48 hours. If you take more than 25 mg of SP Agra and take other alpha-blocking medicines (eg doxazosin, prazosin, terazosin) under different conditions (eg enlarged prostate), separate the time between taking these medicines with more more than 4 hours. Store SP Agra at room temperature at a temperature of 77 degrees F (25 degrees C), away from light and moisture. Quick storage is allowed between 59 and 86 degrees F (15-30 degrees C). Do not store in the bathroom. Keep all medicines out of the reach of children and pets.

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